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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec0148d2bbccc5c2070778de26b52700b08bc92ecf28b4b3b028f01e4ea5530' 
  AND token = '2BiUR+ZYCkRCAzbsDtFfk9j0DgO1zN23vgNZIfAUOuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}