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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef2dee1190b512cf61b0a777333e92c2000e327b547b4756a7e7eef3de98311' 
  AND token = 'P3/weRk86siVaQ001oQrYrurEUFX8oZTsyWqN27Lxhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}