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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b2930ee6bbc8ad2764ab9bb77621efd9921f40faf4e09d5cfa918291cb2a298' 
  AND token = 'Qs+WZtcQ67qH8MnMdoJ77Yin+z1MbrJpTtCL7uPVvxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}