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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72331a6816babb8452e4d3128a6315df1a444e8a5c9a05369972c1a01d57811' 
  AND token = 'SXrvM2SqR3YaqNO+Ufv4FEwqgWh4nlPGyVsofxqXcYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}