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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3c48a22d722c83d5afbacd84e933c051311f6e9a956ecb2f17a73dea749c906' 
  AND token = 'k7ZGSOX9C4mM5KGi4OgWuorSunzfQSowBuw16JNds+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}