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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71549e3fcdee91f0fcef5bd571bca63c255dc22c750b864ba008f097d0165304' 
  AND token = 'f5FY8lrsl/3RpoHNMHjmeAaH55nrQnVxa24bv0rcCns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}