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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09f4b0e4e699bb3203132b2a0a3d26d3d45fee7e7c2bb2897166b2e8a7c26164' 
  AND token = 'yGm861G5OHMN1dRyIuMHFHiDws+1Y2z5/Jq38aWpJQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}