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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cf244e75055f2bd23108f2a21a38b259de2685198dbea2e1c793df6c424f1b5' 
  AND token = '8hAdeLAL4Qg4BMYRrql8CYWB0pdB1qcwXMN7FJu0d0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}