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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60f8f48a1b4e0c6e3e040b7a205e4a40044e25b26952f86bdd3fd3735b8de854' 
  AND token = 'LvfA2I+3eFqrcQeAVGY25VmNMk4+wpFgrG9gOjUb5H4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}