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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57c7c143cf6fb6174a14c9afbadcc0947d8b6b2f2019d7a1270c96eee6b27bf' 
  AND token = 'YdLFmPuywQ5yMiGG+jubLCFawDfGs4CjqOJP3oGWxUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}