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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad1c2b25895e5f61c9014dab546d22ec898d725ac743f5a9e1525413a8e020b7' 
  AND token = 'M46dMGJbdtKoDR6N3U1f8m1iubIcIIIAzkQ7wE5jkgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}