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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a95df1fde1c47b35ffa47231239619cb21c23b16acd875eb705414fce5f6c4bc' 
  AND token = 'UhSVwGlW4beww4KJhE9/alhnk+S6rb54CxmcTgYuSUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}