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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280bb1d1beeaee82ea1e07bc18efb1f9f77dd74888d3b9f716999b54a5b7729d' 
  AND token = '5at5OYmdXq9GOHykBVwDGKLpbbn6p7PSSNKwzhrF8tY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}