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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9aebeb97b3d50795b264b4bab374b09f776ea72ed5a6016b61ee8a2c26bcfd0' 
  AND token = 'Gr4BHDc6rHnsZsHZ/ro3TcQsC5hrTvSoTJcG2STjexY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}