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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61c41c48b1cd520e7cc8d94823b376d74079d30788f1c3dc69c06fcf6e292c31' 
  AND token = 'tPW+4htV+4RDa2M1DUZcltUQjz7KovPGQRg7//L8HDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}