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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37d922210c740c59b048d0309217a978c97da5ec1b7bbd6f3a8d9280fd8836bc' 
  AND token = 'rpm1nCanOzLEAyLxHlTCcQrM8TPd08Wyv/2R4Dvb49s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}