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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25e2f0e92f7b486f46aef2f0fd353a68c57295b72752f87c8141c2e6b0fbeef' 
  AND token = 'up727Vqrt8WhK714EsfXofySJH6UHPSsNfz/YzLbkjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}