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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6c801996e080e33541a0cf1b830f03744e9530f00eb8115991d741f962acd67' 
  AND token = 'nNiHRUnpaoQv39Zp+dpvdlxkQqgPt2ATTCiOBzxKzNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}