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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd013ca2b5616e6709d397d70f9c735c20d27eda22bdf6845d9f10d07ad6edde3' 
  AND token = 'cYlQvZ6oSuuL+2Cgct0g5HLTWZZYGzxG/UO70Z6sWWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}