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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741bbb204eaf3c6e8ecc7ce9888bc16219866e169906aa4b75799c17ecd107bf' 
  AND token = '5mmK3a07fHXth8nfIMPM4btY3eZf0y8WQl7ek1lnNKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}