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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c945c3b0ed3cc29c943a920a9bde99c98923300e09b054f7ae28a8eace2552e' 
  AND token = 'XPCnWWS0BqMZixucVij2bglSfT6dk3CqlM/1IDuR6Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}