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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e11c0d63921178a4b334c9d5d6b2f25656333d9573a44c9702121991c43469f9' 
  AND token = 'mz1AuWcWbAc4juyUCo01mwAs9ronG49Qjy21665/26c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}