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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3d47cd6250e36ff1d7794f9c0080c12aa8661e159542d0cb61aecbfff25df9' 
  AND token = 'UXiAUJhhw7diJM5EWbnLltr7qrs9/F2pWLz4ba1dAwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}