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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9d5bc08ee7854ab103aa7b196e92c12f2499e70d7f69b7f16711da5919a83c6' 
  AND token = 'NMi+gh65IvHVS9F0n9pcmMteRlaipUBocGpU9gTZ5Co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}