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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdc943923be50499177c8a54e32a6c26a09bc4b562518f1f3ebde84a0d1d9a59' 
  AND token = '+c+/noXCMLnOS6j6hZ+QUNWmbToOEoNToS1eAW5FluU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}