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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b115e372d7b40df2f86e2cbffd4041ab1cce618191b96835c80a7df744fdfb9' 
  AND token = 'QkoEg17Tm95+gXLTg+6ahkvF9bUUyGiTIa19x/2r4BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}