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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad45feae3b2df1785abaf7774ec58559d8c1b8c890176f586d0ca5d0a1684169' 
  AND token = 'hRjFRR8r4aFFHR4UwrYXs4RUscc4XEP0PZu8PxzvTpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}