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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e0fa49471215fe5dff6bc686cf497e08379176a7fc699b10a56b8d8b6c05dfa' 
  AND token = 'FJ8bM0Lm6/zsGZLS69dnSgrT1I2h6d+GxwRU3SHK+hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}