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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d2648d748a6b7ee06d23074cc9ed69dae6254119dd2bdfb40810fe0292f59db' 
  AND token = 'nsmZ8JgA7MiQ6QmxLbzzf39rR0x9dxA2DM+ywCgBtlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}