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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2424608c5b39aeb9faf79e71b605aa02a16a262b325c13e2a64e53747de9c85e' 
  AND token = 'NHfyoJj57GtgH2hiOA/yix8bGv8UhLiox/fyaBvGvMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}