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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eccbd0a8504178a0513e66b607d83915abfa12d1cbac1bfe4e86f273fbd7ae6f' 
  AND token = 'tRVNvpqqNfOwx1nELnrWeueNZcIiU6leSDR83pOH4tM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}