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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36c97cf7c33c754c24d76be77c945c937c3ae1ea3dbbee20fd3b090ed936e64b' 
  AND token = 'EjXeq6tOtMVB0oPQyeGoQhpBc6Km+EeHqI2oqNEdt+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}