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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8ae7b2b8a94decc18f87795e8211108667759024de7a4520b338d273dff8d85' 
  AND token = '7ne40N2Biz0yWrqLA9QAsKuE1+RBByj6K4ru2UPlnzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}