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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd114166aee83cd681a467863468010135f1244960ad64c56c9614b82d7c57449' 
  AND token = 'nh1ATuC98Wk4z54Q35ZYFKtYwyCYaE7ga+6I8gP91/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}