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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a05e10a3def999d7b3961d3500b30580689b4abfbc6a8de6ad1de3c2478bb173' 
  AND token = 'FtuHfmquCEp723iNrCEWf98UEQj/f/qPzIS04GzWb/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}