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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42cc5e113a0574eba7f0580552a8e676de04cd1ab9bb6990b49894c689998c67' 
  AND token = 'SsdyJUE4LWVBKA6MIAY4UZwlygE4go3F4E+SuSuht4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}