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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8893c0b576713287f32dc6e205d79d38758b34f883d6e55ca684b6b09ac858c2' 
  AND token = 'VU1DNh+Mi2fQtaZC3tz23k23rkP8fkY9TFJg+nsdH4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}