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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff15c5fe072afc9e84249e5546a3192e1f967a4b050c74d261671fe1d3c2102d' 
  AND token = 'ormvcf7Z1ohWvIBlaFXr8eUiXrZma0KaLsiJ8N3TxGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}