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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b412cda33e5e84a9355ebae2e38d7d9f8310329df21d35d8c7d29e93841c6ec' 
  AND token = 'xDws0DjirMSjk61pqEwuqebHluSkWns4v7H75+htBcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}