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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ae7d6f905333b5d92e2bfbccd297e5180cd1bdf0d7577f837046f88e623213e' 
  AND token = 'V5xqIS2s3MdPaRnoZPx7Q7pU2Uv7eBgotiqTS8vTYuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}