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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44829111207e3ebba312f28927e1c177470d5b952a5dcab7e1c61a60cc2d2221' 
  AND token = 'QU3vgdJuaoSb5ewMhozfwNjcNytDcn/GVmtB/3VuUUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}