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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f543bbb4b25c6a5015fd532eddde422dd6a272a43c24db1f9ba25a5d6117687b' 
  AND token = 'fuQ/blQIDNdFVRBTcY5w6z5zy/cwk/pjts7V0hN0mMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}