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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d4fd8abe6359e4c0214600998509eb8b7c27712f82024b15415dda53a305614' 
  AND token = 'aKmdAVcnySGlKW0KrNsRSOiqUS7t/BX0574TrvCG28Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}