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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4140f86ab5fcde68b497318ce6285ff0e6f78c2d68d2b97a8c246eae34f33cce' 
  AND token = 'efGyg9Sw0rXnoUfheFwY+UleuJQg3ctPk75R3u02b4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}