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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e88b7c194b871d52a2af57d8d36296fa318aaf5e0ccbb2e86c291090dee7566' 
  AND token = 'uzPB0bIhBk5Q+8FLfCNEetfvy+PdQfEfhOOBHp95wnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}