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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3da1ca5466b127a020564aebd8803c19772890f2962c99e6db3d34e5d6ae03a0' 
  AND token = 'vhpxtephqjAx/jpkeIDy7Xko8t4v7HwBNwuJ0TFo+mU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}