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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '464c91b3604a8e1d1c448beccf824af1c6f5ee15b67ef1e5a24e199141caf3e6' 
  AND token = '8P+uPAm5g5IViNRNP+tfxYXEYqjdHJEi8bCtREFGVY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}