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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e801e0ce80d80f7a2efdf9d363820cfb21687162b95942ce987af79fd47588' 
  AND token = '2RFrxJFTHODCBM1AqJSj777f6+SwWBo3UAL2Dwa799Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}