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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d00f63c45b5a7a663d4496a1a60bdf646f52fc0790bf1e0b5730aac839288cf' 
  AND token = 'UJ5UvSQJyJ+hE9EiMjvNsUvT8XUS9eS900IIIlwASxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}