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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '895167f8c0a685810fe0901dea5769cbf95a3f24756b97572ef38b9597c1c55c' 
  AND token = 'YUBtDQFNYTdD+pSLUgS7VEVZ5nLicjx0F0F6tW2CIE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}